Hi FGCU,
When you are over 200 lbs or so I would tend to reduce or minimize the use of 4 lb memory foam (in any mattress including Tempurpedic) and I would also consider higher density base foam (the Dreamfoam uses 1.5 lb base foam) because they will both be more durable under the greater stress of higher weights.
Even if they are the same density … the feel and response of different types of memory foam can vary widely. While the biggest factor in durability is density … the same density memory foams can use different formulations which affects their individual properties. You can read more about this in post #9 here and in post #8 here.
In terms of how they each feel compared to the Tempurpedic Cloud Supreme, the best suggestion would be to talk with them directly. They would be more knowledgeable about the feel and performance of their own mattresses than anyone else.
The Cool supreme also has a better return policy … “just in case” you aren’t happy with the mattress.
The “read first” post I linked earlier includes a link to some of the better online memory foam retailers and manufacturers I’m aware of (which of course included Dreamfoam and Brooklyn Bedding who are both invited members of the site).
Phoenix