Hi okiebirdnerd,
This would be a quality/durability issue not a “comfort” issue (see guideline #4 here and post #2 here about durability). I would tend to use a guideline of “no more than about an inch or so” of lower quality or unknown materials in the upper layers of a mattress and once there are 2" or more of lower quality/density or unknown materials in a mattress it would be a much more risky choice and the lower density foams could be a weak link in the mattress and lead to the premature loss of comfort and/or support.
The quilting foam or other materials used in the quilting will also affect the “feel” of the latex below it (see post #12 here and post #2 here about quilting layers) but you can test to see if a mattress is suitable for you in terms of PPP and how it feels but you can’t “feel” the quality of the materials in a mattress because both lower quality and less durable materials can feel the same as higher quality more durable materials.
Phoenix