Hi landale1,
If you are thinking about designing and building your own DIY mattress out of separate components that are purchased from one or several different sources then the first place I would start is by reading option 3 in post #15 here and the many posts it links to (it’s a bit of reading, but really is worth it to spend some time delving into those posts and links) so that you have more realistic expectations and that you are comfortable with the learning curve, uncertainty, trial and error, or in some cases the higher costs that may be involved in the DIY process.
Your question doesn’t have an exact answer, as quite a bit of this comes down to your personal preferences and perceptions, and your own definition of what might “balance out” one configuration versus another. But I can provide some general information, without getting too technical.
The 3" of plush D65 Dunlop would generally be near the maximum range I’d recommend for a side sleeper, but this is of course a general recommendation. You are correct that using two 2" layers will offer you more versatility and going with D65 over D75 would be a bit more of a “typical” configuration. Which might feel best to you would of course be determined through your own personal testing. While Dunlop does have a higher compression modulus than Talalay and the D65 in 3" would “firm up” more in areas compressed more than 25%, it would not feel as firm overall as the D65/D75 combination you mentioned.
There’s really no way to know unless you’ve tested similar reference mattresses which contain similar combinations of materials if you might prefer one of these combinations over the other. All of these layers (including the pocketed spring unit) will compress simultaneously and they will each compress to different percentages of their thickness depending on their position on the mattress, the firmness of each layer, the compression modulus of the material, the thickness of each layer, and the compression force that they are exposed to (which depends on the weight of the part of the body in contact with the mattress and the surface area that is bearing that weight which is constantly changing as you sink into the mattress more or change sleep positions).
Even the softest latex won’t tend to “bottom out”, but you may tend to “feel through” the softer D65 3" layer to the transition to the innerspring unit, versus the D65/D75 combination where the materials may “bend into” each other a bit more gradually.
Without personal testing and going through the learning curve of becoming familiar enough with different types of materials and layering and how they work in combination with each other to predict how a certain layering may work, I often suggest going with the suggestions of a knowledgeable retailer or manufacturer who is familiar with how the different options they offer fits the “averages” of people who may be similar to you, or mimicking combinations that you’ve tested and are currently offered by other manufacturers. While the question you asked seems simple on the surface, it actually is quite complex and there are experts within the industry who spend their lives analyzing how different layerings work together. Being able to rearrange layers, as with the D65/D75 example, while it does introduce extra variables into the equation, does give you more options to “fine-tune” your design.
You’re correct that there is less noticeable difference in surface comfort the farther away you are removed from the uppermost layers. Differences in the second 2" layer in your example will definitely be noticeable, but will not have as great of an impact in initial comfort as a change in the uppermost layer.
There is more about primary or “deep” support and secondary or “surface” support and their relationship to firmness and pressure relief and the “roles” of different layers in a mattress in post #2 here and in post #4 here that may be helpful in clarifying the difference between “support” and “pressure relief” and “feel”.
Phoenix