Hi YSPhotog.
Welcome to our Mattress Forum. 
A DIY mattress is always a fun and challenging experience, and it’s great that you’re looking to build something that will offer both longevity and comfort to your son.
Looking at the specifications on the Serta iSeries 1000 Hybrid, especially for a “big boy like his father” I would have some concerns regarding the durability for this unit and trying to replicate the feel of this mattress using its specs. You may want to check out the Mattress Durability Guidelines for your son’s DIY.
There is some fairly detailed but generic information in the mattresses section of the site that will give you some insights into the theory behind mattress layering and design for different body types and sleeping styles but these are not specific to any individual person. Each different design and combination of materials can lead to a different answer … especially when there are unique needs, preferences, and challenges that may be very different from the norm or any “averages”. For example, I’ve noticed you added about 2" to the comfort layer. Was that decision based on something specific, or through mattress testing, etc?
I’d also keep in mind that attempting to find something that is exactly the same is often a frustrating and futile exercise especially if you are trying to do that on your own. There is more information in post #9 here about the different ways that one mattress can “match” or “approximate” another one. Every layer and component in a mattress (including the cover and any quilting materials) will affect the feel and performance of every other layer and component and the mattress “as a whole” so unless you are able to find another mattress that uses exactly the same type of materials, components, cover and quilting, layer thicknesses, layer firmnesses, and overall design (which would be fairly unlikely) then there really isn’t a reliable way to match one mattress to another one in terms of “comfort”, firmness, and PPP (Posture and alignment, Pressure relief, and your Personal preferences) based on the specifications of the mattresses (even assuming that you can find out all the specifications you would need for both mattresses you are comparing in the first place).
This being said I think that you’d be better served by contacting one of our mattress experts that offer DIY options to help you with your build. They would be the best to help you approximate a mattress feel based on all the specs and your personal needs and preferences you may provide.
The layers that will affect whether or not he feels he’s sinking too deeply will be the two 2" foam comfort layers. The 1" is a medium-firm buffer/transition layer that is likely contributing to some secondary support. In some mattress constructions, particularly those with thinner comfort layers, they have secondary functions of helping the comfort layers to form a pressure relieving cradle and helping to hold up the more recessed parts of the body profile such as the lumbar area. You may wish to revisit the The basic functions of a mattress article for clarifying these concepts.
We have very experienced DIY experts on the forum. A few who come to mind are DIY Natural Bedding, Arizona Premium. You are welcome to contact Arizona Premium in their dedicated forum, or you can reach out to DIY Natural Bedding and ask them to weigh in here.
Looking forward to how your DIY journey unfolds!
Phoenix