Hi DrKat,
Each person can be unique and what works well for one person can be completely unsuitable for another so your highest chance of success is always a more detailed conversation with the manufacturer. It can also help to do some local testing as a reference point on mattresses that are similar to the one you are considering (if there are any available locally) and if you let me know your city or zip code I’d be happy to let you know of any of the better options or possibilities I’m aware of in your area (all I know is that you are in South Texas).
If your husband is 350 lbs I would also make sure that the mattress is suitable for his higher weight and it may be worth considering one of the Dreamfoam or Brooklyn Bedding mattresses (their sister company) with thicker layers of latex along with a higher density base foam which may be both more durable and more suitable for much higher weight ranges.
Post #3 here and some of the posts it links to may also be worthwhile reading for someone that is in a much higher weight range.
Phoenix