Hi bcfrederick95,
Both latex and innersprings would be very “safe” choices with no offgassing but they would have a very different feel and response.
The choice between them would be based on personal preference and would depend on the complete design of the mattress and how well it worked for you in terms of PPP (Posture and alignment, Pressure relief, and Personal preferences). both an all latex and a latex / innerspring hybrid can make very good choices.
You can read about some of the more technical differences between them in post #2 here.
Phoenix