Hi zman11,
[quote]Can you provide recommendations w.r.t. number of layers and perhaps latex material type?
Given the online purchase would like to minimize the layer return back and forth. While I’ll chat with several manufacturers, I’m wondering if anyone has gone through the process and if they wouldn’t mind sharing so I could benefit from their experience.[/quote]
There are too many unknowns, variables, and individual preferences involved for anyone to make specific mattress suggestions for someone based on a formula, mattress specs, or "theory at a distance else although I’m always happy with “how” to choose (see mattress firmness/comfort levels in post #2 here). I would also be very cautious about using the preferences of others as a way to choose a mattress because a mattress that works perfectly for one person may be completely unsuitable for someone else.
The first place I would start is the tutorial post here which has all the basic information, steps, and guidelines that can help you make the best possible and most suitable choices for you … and know how to avoid the worst ones.
@ Nevermore
Great suggestions … thanks for taking the time to share them 
Phoenix