Hi sbperseus,
Welcome … and I’m glad the site could help you 
That would really depend on the specific benefits you are referring to but you would certainly feel the properties of the latex layer in the mattress and you would also notice a difference if you replaced the 2" of latex with a different material.
All the layers and components in a mattress (including the cover and quilting) will affect the feel and performance of every other layer in a mattress above and below it and the mattress “as a whole” to different degrees so what you feel on a mattress is the combined effect of all the layers more than the effects of just a single layer.
In very general terms though … the properties and firmness of materials and components that are closer to the top surface of a mattress will tend to have a bigger effect on the overall “feel” and firmness of a mattress than materials that are deeper in the mattress, thicker layers will contribute more of their feel and firmness to the mattress than thinner layers, and a thinner layer would “allow” more of the feel and properties of the layer or component underneath it to “come through” than a thicker layer.
Having said all that … the only way to know for certain whether any mattress is a good “match” for you in terms of comfort, firmness, and PPP (Posture and alignment, Pressure relief, and your own Personal preferences) and how well you will sleep on a mattress will be based on your own careful testing (hopefully using the testing guidelines in step 4 of the tutorial) or your own personal experience when you sleep on it.
[quote]Also, are the lower density polyfoam layers too thick?
Mattress layers (top to bottom)
-Dual knitted cover
-3/8 " polyfoam in the quilted layer (1.5 lb density)
-2" graphite latex
-1" memory foam (4 lb density)
-1" polyfoam (1.5 lb density) (was told this is to enclose the pocket coils in a box)
-14" micro pocketed coils
-1" polyfoam (1.5 lb density) (was told this is to enclose the pocket coils in a box)[/quote]
I doubt that the micro pocket coils are 14" tall (I would guess you probably meant 1.4") and it also looks like the support core of the mattress is missing in your description.
Assuming that the only missing layers and components are the support core of the mattress (which I’m guessing would probably be some kind of innerspring) and assuming that all the layer and component thicknesses add up to the thickness of the mattress and you have confirmed that there are no other missing layers or components in the description … then there are no lower quality materials or weak links would compromise the durability or useful life of the mattress relative to BMI ranges that are under about 30.
If you have done some careful testing and are confident that the mattress is a good match for you in terms of comfort, firmness, and PPP and that you are likely to sleep well on it and it also compares well to your other finalists based on all the other parts of your personal value equation that are most important to you then it would certainly be worth considering.
Phoenix